Test Offerings

Millennium PGTSM Offerings

Millennium Pharmacogenetic Testing (PGT)SM can help health care professionals more effectively personalize treatment by identifying patients who may benefit from a modified drug selection or dose of certain prescribed medications.

Millennium PGT can be ordered by medical specialty, by medication/medication class, and by individual gene-drug pairs.

Classifications Medication Genes
Addiction Therapy Naltrexone OPRM1
Anticoagulants Warfarin CYP2C9, VKORC1
Antidepressants, SSRI/SNRI L-methylfolate MTHFR
Paroxetine, Venlafaxine CYP2D6
Citalopram, Escitalopram, Sertraline CYP2C19
Antidepressants, TCA Amitriptyline, Clomipramine, Doxepin, Imipramine CYP2C19, CYP2D6
Desipramine, Nortriptyline CYP2D6
Antipsychotics Aripiprazole, Haloperidol, Risperidone CYP2D6
Atomoxetine Atomoxetine CYP2D6
Benzodiazepines Diazepam CYP2C19, UGT2B15
Lorazepam, Oxazepam UGT2B15
Methadone Methadone CYP2B6
Muscle Relaxants Carisoprodol CYP2C19
NSAIDs Celecoxib CYP2C9
Opioids Fentanyl CYP3A4, CYP3A5, OPRM1
Morphine COMT, OPRM1
Codeine COMT, CYP2D6, OPRM1
Hydrocodone, Oxycodone, Tramadol CYP2D6
Platelet Inhibitors Clopidogrel CYP2C19

Millennium UDTSM & OFTSM Offerings

Medication monitoring and drug detection services from Millennium Health ensure that clinicians can choose tests individually, based on medical necessity, rather than being obligated to use a one-size-fits-all, pre-set panel of tests.

Our test menu continues to expand, reflecting the most current prescribed medications and an ever evolving list of illicit substances, emerging medications and drugs. Our research and development team of preeminent clinical and analytical chemists are constantly designing, developing and implementing new assays.

We advanced our LC-MS/MS technology to provide drug specific identification and quantification for more than 95 drugs and metabolites using a minimal volume (1-2mL useable urine) of specimen. This allows us to identify whether more than 375 brand name drugs may be present in patient samples.

Natural & Semi Synthetic Opioids

  • Codeine
  • Morphine
  • Hydrocodone
  • Norhydrocodone
  • Hydromorphone
  • Oxycodone
  • Noroxycodone
  • Oxymorphone
  • Buprenorphine
  • Norbuprenorphine
  • Buprenorphine (Transdermal, i.e. Butrans®)

Synthetic Opioids

  • Fentanyl
  • Norfentanyl
  • Methadone
  • EDDP (methadone metabolite)
  • Propoxyphene
  • Norpropoxyphene
  • Tramadol
  • Tapentadol
  • Meperidine
  • Normeperidine


  • Alpha-hydroxyalprazolam
  • 7-Amino-clonazepam
  • Lorazepam
  • Nordiazepam
  • Temazepam
  • Oxazepam
  • Diazepam* (OF Only)


  • Amphetamine
  • Methylphenidate
  • Phentermine
  • Ritalinic Acid

Tricyclic Antidepressants

  • Amitriptyline
  • Nortriptyline
  • Imipramine
  • Desipramine
  • Cyclobenzaprine

Selective Serotonin Reuptake Inhibitors (SSRIs)

  • Citalopram/Escitalopram
  • N-Desmethylcitalopram
  • Hydroxybupropion
  • Duloxetine
  • Fluoxetine
  • Norfluoxetine
  • Paroxetine
  • Venlafaxine
  • Desmethylvenlafaxine


  • Phenobarbital
  • Secobarbital
  • Butalbital

Muscle Relaxants

  • Carisoprodol
  • Meprobamate


  • Gabapentin
  • Pregabalin

Alcohol/Alcohol Metabolites

  • Alcohol/Ethanol**
  • Ethyl Glucuronide
  • Ethyl Sulfate

Illicit Drugs

  • Cocaine* (OF Only)
  • Benzoylecgonine (cocaine metabolite)
  • cTHC (marijuana metabolite)
  • MDMA (ecstasy)
  • Phencyclidine (PCP)
  • Methamphetamine
  • 6-MAM (Heroin metabolite)
  • Mitragynine (Kratom alkaloid)
  • 7-OH Mitragynine (Kratom alkaloid)

Specimen Validity Testing ***

  • Creatinine
  • Oxidants (nitrite)
  • pH
  • Specific Gravity

Synthetic Cannabinoids (Spice)

  • AM2201-OH
  • MAM2201-OH
  • JWH018-OH
  • JWH073-OH
  • JWH081-OH
  • JWH122-OH
  • JWH210-COOH
  • JWH250-OH
  • RCS4-M9
  • RCS4-OH
  • UR144/XLR11 metabolite

Cathinones (Bath Salts)

  • MDPV
  • Mephedrone
  • Methylone


  • Aripiprazole
  • Dehydroaripiprazole
  • Clozapine
  • N-Desmethylclozapine
  • Haloperidol
  • Haloperidol metabolite
  • Olanzapine
  • Quetiapine
  • Norquetiapine
  • Risperidone
  • Hydroxyrisperidone


  • Dextromethorphan
  • Dextrorphan (Dextromethorphan metabolite)
  • Cotinine**
  • Ketamine
  • Norketamine
  • Naltrexone
  • Naltrexol (Naltrexone metabolite)

(*) Drugs and/or metabolites available via oral fluid testing.

(**)Test available as an immunoassay.

(***) Tests are each billed separately.