Definitive Oral Fluid Drug Testing with Millennium OFT

Benefits of Oral Fluid Drug Testing

Oral fluid drug testing (OFT) is a convenient alternative to urine drug testing (UDT). The clinical comparability of UDT with OFT has been shown in several studies,1,2 including a key study published by West et al.3 The Substance Abuse and Mental Health Services Administration (SAMHSA) has endorsed OFT for use in a variety of clinical settings.

Advantages of OFT include:

  • Convenient-no restroom needed
  • Specimen collection observed, mitigating tampering
  • Helpful for patients unable to provide a urine specimen (e.g., in renal failure or due to incontinence)
  • Oral fluid collection may be more acceptable to staff and patients

We also offer urine drug testing which provides definitive detection of more than 100 drugs and metabolites encompassing over 400 brand name drugs.

Test Menu Offerings for Millennium OFT

Medication monitoring and drug detection services from Millennium Health ensure that clinicians can choose tests individually, based on medical necessity, rather than being obligated to use a one-size-fits-all, pre-set panel of tests.

Collecting a Specimen for an Oral Fluid Drug Test Is Simple and Convenient

Open the Quantisal™ oral fluid collection device packaging

Hold the collection wand handle & position the cotton pad under the patient’s tongue

The Quantisal volume adequacy indicator turns blue to indicate the collection is finished (4-7 minutes)

Put the collection wand into transport tube & secure the red cap

Affix the specimen ID label to the transport tube

Send the specimen to Millennium Health within 2 days post collection

Millennium Health requires the use of a Quantisal™ Oral Fluid Collection Device. This is distributed by our e-commerce supplier, American Solutions for Business (ASB). The content above is only intended as a quick reference and does not replace the ‘Instructions for Use’ supplied by the device manufacturer and the Millennium Health Medication Monitoring Specimen Collection, Ordering and Shipping Manual.

Our Comprehensive RADAR® Report

Our RADAR Report for oral fluid drug testing provides clinically actionable results to support confident therapeutic decisions with:

  • Clinical interpretation comments on results to better inform clinical decision making
  • Customizable report settings that meet the needs of individual practices

RADAR Hotline

Consult with our expert toxicologists and clinical pharmacists available for real-time discussion, results interpretation, education and training Monday through Friday on the RADAR Hotline (866) 866-0605.


  1. V. Vindenes, et al. Oral Fluid is a Viable Alternative for Monitoring Drug Abuse: Detection of Drugs in Oral Fluid by Liquid Chromatography-Tandem Mass Spectrometry and Comparison to the Results from Urine Samples from Patients Treated with Methadone or Buprenorphine. J. Anal. Toxicol. 2011, 35:32-39.
  2. C. Moore, D. Crouch. Oral Fluid for the detection of drugs of abuse using immunoassay and LC-MS/MS. Bioanalysis (2013) 2(12), 1555-1569.
  3. West R, Mikel C, Hofilena D, Guevara M. Positivity rates of drugs in patients treated for opioid dependence with buprenorphine: A comparison of oral fluid and urine using paired collections and LC-MS/MS. Drug Alcohol Depend. 2018, 193:183-191.