CDC Dashboard

Millennium Health and CDC Collaborate on Clinical Drug Test Dashboard

Offering timely insights on shifting drug use trends to inform targeted, life-saving strategiesRead More

Signals Report Vol. 8

Fentanyl Overdose Deaths Plummet but Unchecked Illicit Stimulant Use Threatens to Reshape America’s Drug Use Epidemic

Millennium Health Signals Report shows Illicit stimulant use increased virtually everywhere in the U.S. from 2024 to 2025 challenging clinicians and complicating efforts to save lives.Read More

Gabapentin Study

Use of gabapentin with or without a prescription in substance use treatment settings: A national analysis of urine drug testing data, 2016-2023

Matthew S. Ellis, Ph.D., Penn Whitley, B.A., Steven D. Passik, Ph.D. Drug and Alcohol Dependence 279 (2026) 113020; https://doi.org/10.1016/j.drugalcdep.2026.113020Read More

UnitedHealthcare Preferred Lab Network

Millennium Health Selected for the UnitedHealthcare Preferred Lab Network

SAN DIEGO, Calif. – November 6, 2025 – For the sixth year in a row, Millennium Health has been chosen to be a part of the UnitedHealthcare Preferred Lab Network (PLN).Read More

Signals Report Vol. 7.1

Cannabis Use Detection, Concentrations Rise Among Young People; Gender Gap in Cannabis Use Narrows

Data from clinical drug testing laboratory Millennium Health reveal worrisome trends among patients who have a substance use disorder

SAN DIEGO, Calif. – October 13, 2025 – Cannabis use has become more common among patients with a substance use disorder (SUD) and the levels of tetrahydrocannabinol (THC) detected in urine have increased across all age groups since 2019. Read More

JAMA Network Open Study

Urine Drug Testing Data Can Provide Timely Estimates of Overdose Death, JAMA Network Open Study Shows

Millennium Health, Ohio State University researchers say drug test data could “close the gap” in the timeliness of reporting overdose mortality

SAN DIEGO, Calif. – June 9, 2025 – The availability of overdose mortality data generally lags by up to 6 months, hindering public health efforts to address the crisis in the present. A study published in JAMA Network Open, co-authored by researchers at The Ohio State University College of Medicine and Millennium Health (MH), demonstrates that aggregated urine drug testing data can be used to estimate timely overdose death trends, presenting an opportunity to “close the gap” in reporting recent overdose mortality trends. Read More

Signals Report Vol. 7

Fentanyl Use Declines in 2024 but People Who Use Fentanyl are Increasingly Using Heroin, Methamphetamine

Millennium Health Signals Report™ highlights the continued evolution of polysubstance use

SAN DIEGO, Calif. – February 11, 2025 – The latest Signals Report from Millennium Health highlights that fentanyl detection in urine drug tests has fallen more than 12% from its 2022 peak but fentanyl-associated polysubstance use remains a significant and constantly evolving threat.Read More

JAMA Network Open Study

New Study Reveals Unprecedented Increases in Fentanyl and Stimulant Concentrations in Urine Drug Test Results

SAN DIEGO, Calif. – October 24, 2024 – A study published in JAMA Network Open, led by Andrew Huhn, PhD, MBA, Associate Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine, Kelly Dunn, PhD, MBA, Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine, and co-authored by Millennium Health researchers, illustrates striking increases in the amounts of illicit fentanyl, methamphetamine, and cocaine detected in urine drug testing (UDT) specimens since 2013. The analysis showed that the concentrations of fentanyl and methamphetamine were 8.3 and 5.2 times higher, respectively, in 2023 compared to 2013 (Figure). Cocaine concentrations also doubled across this time period, whereas those for heroin fell by more than half.Read More

Carfentanil Extends Deadly Reach

Millennium Health Signals Alert™ Shows Carfentanil Extends Deadly Reach

New report identifies concerning uptick in detections of the lethal fentanyl analogue across the U.S. since reemerging in 2023

SAN DIEGO, Calif. – September 24, 2024 – Carfentanil was detected 134 times in urine drug test (UDT) results in 21 states from July 2023 to June 2024 (see Map) compared to only 11 times in six states during the preceding three years.Read More