Signals Report Volume 6

Methamphetamine Use Reaches All-Time High in People Who Use Fentanyl with No Signs of Slowing, Adding Fuel to U.S. Fentanyl Crisis

Millennium Health Signals Report™ illustrates changing nature of polysubstance use

SAN DIEGO, Calif. – February 21, 2024 – According to Millennium Health’s Signals Report, a staggering 60% of specimens in 2023 from patients who have used fentanyl also contained methamphetamine, an increase of 875% since 2015.Read More

Millennium Health in the News

SAN DIEGO, Calif. – February 20, 2024In our efforts to raise awareness of the dangers of fentanyl and other illicit drugs, we regularly work with the media to share information nationally and within our local communities. Read More

Signals Alert: Carfentanil

Millennium Health Signals Alert™ Shows Reemergence of Deadly Carfentanil

Carfentanil detections in urine drug tests have increased from coast to coast in 2023 and may exacerbate the nation’s overdose crisis

SAN DIEGO, Calif. – November 2, 2023 – Carfentanil is one of the most potent fentanyl analogues known; 100 times more potent than fentanyl and 10,000 times more potent than morphine.Read More

Signals Report: Xylazine

Xylazine Has Spread to Every Region of the Country, Millennium Health Signals Report™ Shows

Xylazine, fentanyl and other potentially lethal substances frequently found together, report from more than 160,000 urine drug tests demonstrates

SAN DIEGO, Calif. – September 14, 2023 – According to the Millennium Health Signals Report released today, the powerful, veterinary tranquilizer xylazine—also known as “tranq”—was detected in urine drug tests from every region of the country, with the highest rates in the Eastern U.S. This analysis of the nationwide spread of xylazine is the most current and substantiative to date since xylazine use rose to prominence.Read More

Signals Alert: Parafluorofentanyl

Millennium Health Signals AlertIdentifies Surge of Parafluorofentanyl in the Western U.S.

Clinicians and public health officials in the West should maintain awareness of parafluorofentanyl use in their communities

SAN DIEGO, Calif. – September 11, 2023 – According to an analysis of over 90,000 urine drug test results, use of the potent fentanyl analogue, parafluorofentanyl, has increased dramatically in the Western U.S.Read More

Fentanyl Awareness Event

Rep. Scott Peters, Millennium Health and Others Gather to Urge Awareness on Fentanyl Risks as Students Return to School

SAN DIEGO, Calif. – September 5, 2023 – Fentanyl is a deadly synthetic opioid that has infiltrated every community in America, killing tens of thousands along the way, including many children and teens.Read More

JAMA Psychiatry Study

Clinicians Identify Buprenorphine “Spiking” In JAMA Psychiatry Study Supported by Millennium Health Researchers

SAN DIEGO, Calif. – March 22, 2023 – A JAMA Psychiatry study, led by Jarratt D. Pytell, MD, MHS, Department of Medicine, University of Colorado School of Medicine, and co-authored by Brendan Saloner, PhD, Johns Hopkins Bloomberg School of Public Health, Department of Health Policy and Management, and Millennium Health researchers calls attention to factors associated with patients who have urine drug test (UDT) samples suggestive of buprenorphine “ADD-IN” (commonly referred to as “spiking”). Read More

Signals Report Vol. 5

Fentanyl Is Widening Grip on the Nation as Western Presence and Detection with Other Drugs Increase to Record Highs, Millennium Health Signals Report™ Shows

Fentanyl co-detection in individuals using heroin, prescription opioids, methamphetamine or cocaine reached historic levels in 2022; Drug test data also show evolution of dangerous fentanyl analogues, with geographical differences

SAN DIEGO, Calif. – February 21, 2023 – Detection of fentanyl in urine drug test (UDT) specimens remains near historic highs and fentanyl co-detection in individuals using heroin, prescription opioids, methamphetamine, or cocaine has reached new heights, according to the Millennium Health Signals Report released today.

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